Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342621 | 0.92 | ALDH1A1 (0.40) | ALDH1A1ALOX15IDO1MEN1KMT2A | |
| SCHEMBL9343559 | 0.84 | ALDH1A1 (0.39) | ALDH1A1ALOX15MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9342887 | 0.84 | EPHX2 (0.36) | ALDH1A1IDO1MEN1KMT2AMAPK1 | |
| SCHEMBL9346997 | 0.76 | EPHX2 (0.39) | IDO1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL9347008 | 0.75 | BCL2 (0.32) | ALDH1A1ALOX15HTT | |
| SCHEMBL9342628 | 0.74 | ALDH1A1 (0.48) | ALDH1A1ALOX15KMT2AESR1NR4A2 | |
| SCHEMBL9347074 | 0.74 | ALDH1A1 (0.48) | ALDH1A1ALOX15KMT2AESR1NR4A2 | |
| SCHEMBL9875215 | 0.72 | ALDH1A1 (0.50) | ALDH1A1ALOX15MEN1KMT2AESR1 | |
| SCHEMBL9347004 | 0.70 | ALDH1A1 (0.48) | ALDH1A1ALOX15IDO1CYP2C19NR4A2 | |
| SCHEMBL22519886 | 0.69 | HTT (0.61) | ALDH1A1IDO1MAPK1MRGPRX4CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328643-B1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO CORP (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5043142-A | Measuring peroxide-active substances | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0328643-A1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO KABUSHIKI KAISHA (JP) | 1989-08-23 | — | — | EP | disclosed |