Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342887 | 0.92 | EPHX2 (0.36) | EPHX2NR1H4MRGPRX4IDO1CYP2C19 | |
| SCHEMBL9342621 | 0.83 | ALDH1A1 (0.40) | EPHX2NR1H4MRGPRX4IDO1CYP2C19 | |
| SCHEMBL1990423 | 0.80 | EPHX2 (0.39) | EPHX2NR1H4CYP2C19MEN1KMT2A | |
| SCHEMBL4831766 | 0.80 | PNMT (0.41) | EPHX2NR1H4CYP2C19MEN1KMT2A | |
| SCHEMBL27894448 | 0.77 | EPHX2 (0.38) | EPHX2NR1H4MRGPRX4CYP2C19MEN1 | |
| SCHEMBL9344472 | 0.76 | ALDH1A1 (0.37) | EPHX2NR1H4MRGPRX4IDO1CYP2C19 | |
| SCHEMBL10600692 | 0.74 | TSHR (0.56) | MEN1KMT2AARTP53CYP3A4 | |
| SCHEMBL9342681 | 0.74 | CHRM3 (0.35) | EPHX2NR1H4MEN1KMT2AAR | |
| SCHEMBL9347622 | 0.72 | TSHR (0.46) | MRGPRX4ARTP53MAPTMAPK1 | |
| SCHEMBL9347635 | 0.71 | BCL2 (0.33) | EPHX2NR1H4USP2CYP3A4P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328643-B1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO CORP (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5043142-A | Measuring peroxide-active substances | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-27 | — | — | US | disclosed |
| EP-0328643-A1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO KABUSHIKI KAISHA (JP) | 1989-08-23 | — | — | EP | disclosed |