Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555636 | 0.92 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL27787118 | 0.89 | GAA (0.60) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL9303102 | 0.88 | ALDH1A1 (0.51) | LMNAALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL9518912 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL5765803 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| Malonic Acid SCHEMBL8982152 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL6141237 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL11094410 | 0.86 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL21652695 | 0.85 | MGAM (0.62) | ALDH1A1MAPTGAAL3MBTL1MAPK1 | |
| SCHEMBL7903564 | 0.85 | ALDH1A1 (0.51) | LMNAALDH1A1MAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784520-B | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2014-07-02 | — | — | CN | disclosed |
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |
| EP-0394957-B1 | Crystalline form of magnesium salt of mono-p-nitrobenzyl malonate and process for producing the same | NIPPON KAYAKU KK (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5087734-A | CRYSTAL MODIFICATION OF MAGNESIUM SALT OF MONO-P-NITROBENZYL MALONATE AND PROCESS FOR PRODUCING THE SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0394957-A2 | Crystalline form of magnesium salt of mono-p-nitrobenzyl malonate and process for producing the same | Nippon Kayaku Kabushiki Kaisha (JP) | 1990-10-31 | — | — | EP | disclosed |