Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7892509 | 0.88 | GAA (0.54) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL9344653 | 0.85 | LMNA (0.57) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL1555636 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL7982908 | 0.83 | HTR2A (0.52) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL9518912 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL5765803 | 0.80 | ALDH1A1 (0.57) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL27787118 | 0.80 | GAA (0.60) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL11094410 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL6141237 | 0.80 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAL3MBTL1RAB9A | |
| SCHEMBL10402699 | 0.80 | HTR2A (0.51) | ALDH1A1MAPTL3MBTL1RAB9AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197774-B1 | THERAPY FOR ASTHMA, SKIN DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |