SCHEMBL9344656

SCHEMBL9344656

O=C(COc1ccccc1)NC(=O)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.72
KMT2A Q03164 5/20 0.58
MEN1 O00255 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
GAA P10253 2/20 0.58
MAPT P10636 2/20 0.58
LMNA P02545 2/20 0.58
APOBEC3G Q9HC16 1/20 0.58
KDM4E B2RXH2 1/20 0.58
ALPL P05186 1/20 0.57
ALPI P09923 1/20 0.57
ALPG P10696 1/20 0.57
RAB9A P51151 3/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
NPC1 O15118 3/20 0.56
HPGD P15428 2/20 0.56
ALOX15 P16050 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10903296 0.87 KMT2A (0.67) ALDH1A1KMT2AMEN1GAALMNA
SCHEMBL10414788 0.86 ALDH1A1 (0.59) ALDH1A1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL10964144 0.79 KMT2A (0.57) ALDH1A1KMT2AMEN1GAAMAPT
SCHEMBL6186553 0.77 KMT2A (0.56) ALDH1A1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL27711498 0.77 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL28946812 0.77 ATM (0.60) ALDH1A1SMN1; SMN2KDM4ERAB9AL3MBTL1
SCHEMBL7699974 0.77 ALDH1A1 (0.57) ALDH1A1KMT2AMEN1SMN1; SMN2GAA
SCHEMBL216783 0.77 KMT2A (0.65) KMT2AMEN1GAAALPLALPI
SCHEMBL11058212 0.76 KMT2A (0.62) ALDH1A1KMT2AMEN1GAAMAPT
SCHEMBL2858346 0.76 PKM (0.63) ALDH1A1KMT2AMEN1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0357409-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
US-4994431-A Containing colorless dye precursor, color developer and 1-alkoxy-phenoxy-2-aryloxypropane sensitizer; preservation stability, high sensitivity FUJI PHOTO FILM CO., LTD. (JP) 1991-02-19 US disclosed
EP-0357409-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed