SCHEMBL9344664

SCHEMBL9344664

C=CCC(C(=C)C(=O)O)[Si](Cl)(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.36
GRIK2 Q13002 2/20 0.36
CYP2C19 P33261 1/20 0.32
CPA1 P15085 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7905059 0.85 GRIK1 (0.34) GRIK1GRIK2CYP2C19CPA1
SCHEMBL6442149 0.76 GRIK1 (0.30) GRIK1GRIK2
SCHEMBL7649349 0.72 GRIK1 (0.35) GRIK1GRIK2CYP2C19CPA1
SCHEMBL362182 0.72 GRIK1 (0.47) GRIK1GRIK2CYP2C19CPA1
SCHEMBL902141 0.70 CYP2C19 (0.39) GRIK1GRIK2CYP2C19CPA1
SCHEMBL31199 0.70 CYP2C19 (0.39) GRIK1GRIK2CYP2C19CPA1
SCHEMBL253739 0.70 GRIK1 (0.41) GRIK1GRIK2CYP2C19CPA1
SCHEMBL278696 0.70 MAPT (0.37) GRIK1GRIK2CYP2C19CPA1
Vinyl Chloride SCHEMBL4029780 0.69 CYP2C19 (0.36) GRIK1GRIK2CYP2C19CPA1
SCHEMBL6442137 0.68 GRIK1 (0.35) GRIK1GRIK2CYP2C19CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323436-B1 Method for preparing and stabilizing acryl-functional halosilanes DOW CORNING (US) 1994-06-22 EP disclosed
EP-0323436-A2 Method for preparing and stabilizing acryl-functional halosilanes DOW CORNING CORPORATION (US) 1989-07-05 EP disclosed
US-4780555-A USING PLATINUM HYDROSILATION CATALYST AND PHENOTHIAZINE DOW CORNING CORPORATION (US) 1988-10-25 US disclosed