SCHEMBL7905059

SCHEMBL7905059

C=CCC(C(=C)C(=O)O)[Si](C)(C)Cl

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 2/20 0.34
CYP2C19 P33261 1/20 0.33
CPA1 P15085 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9344664 0.85 GRIK1 (0.36) GRIK1GRIK2CYP2C19CPA1
SCHEMBL6442149 0.76 GRIK1 (0.30) GRIK1GRIK2
SCHEMBL8944185 0.70 GRIK1 (0.35) GRIK1GRIK2CYP2C19CPA1
SCHEMBL8617632 0.70 GRIK1 (0.39) GRIK1GRIK2CYP2C19CPA1
SCHEMBL7649349 0.70 GRIK1 (0.35) GRIK1GRIK2CYP2C19CPA1
SCHEMBL362182 0.69 GRIK1 (0.47) GRIK1GRIK2CYP2C19CPA1
Propane SCHEMBL15303734 0.68 GRIK1 (0.42) GRIK1GRIK2CYP2C19CPA1
SCHEMBL10989774 0.67 GRIK1 (0.32) GRIK1GRIK2CYP2C19CPA1
SCHEMBL902141 0.67 CYP2C19 (0.39) GRIK1GRIK2CYP2C19CPA1
SCHEMBL31199 0.67 CYP2C19 (0.39) GRIK1GRIK2CYP2C19CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6255424-B1 COUPLING POLYMERIC PRECURSOR SEGMENTS, EACH HAVING LIVING END CAPABLE OF REACTING IN POLYMERIZATION REACTION, TOGETHER IN CONVERGENT MANNER INVOLVING REACTION OF MULTIFUNCTIONAL COUPLING AGENT TO FORM HYPERBRANCHED STRUCTURE COLORADO SCHOOL OF MINES 2001-07-03 US disclosed