SCHEMBL9344739

SCHEMBL9344739

CC[C@H]1CC[C@H]([C@H]2CC[C@H](CCOc3ccccc3)CC2)CC1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TEAD1 P28347 1/20 0.47
TEAD3 Q99594 1/20 0.47
NFE2L2 Q16236 1/20 0.44
KCNA3 P22001 1/20 0.42
LTA4H P09960 2/20 0.42
CHRNB2 P17787 2/20 0.41
CHRNB4 P30926 2/20 0.41
CHRNA3 P32297 2/20 0.41
CHRNA7 P36544 2/20 0.41
CHRNA4 P43681 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9454566 1.00 TEAD1 (0.47) TEAD1TEAD3NFE2L2KCNA3LTA4H
SCHEMBL9349642 0.95 TEAD1 (0.50) TEAD1TEAD3NFE2L2KCNA3LTA4H
SCHEMBL9349635 0.95 TEAD1 (0.50) TEAD1TEAD3NFE2L2KCNA3LTA4H
SCHEMBL9346506 0.90 TEAD1 (0.47) TEAD1TEAD3NFE2L2KCNA3LTA4H
SCHEMBL9346498 0.90 TEAD1 (0.47) TEAD1TEAD3NFE2L2KCNA3LTA4H
SCHEMBL4980425 0.86 TEAD1 (0.56) TEAD1TEAD3NFE2L2KCNA3TAAR1
SCHEMBL8529857 0.85 LTA4H (0.50) TEAD1TEAD3NFE2L2KCNA3LTA4H
SCHEMBL8081852 0.85 LTA4H (0.50) TEAD1TEAD3NFE2L2KCNA3LTA4H
SCHEMBL9344646 0.83 CARM1 (0.49)
SCHEMBL9344650 0.83 CARM1 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393636-B1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORP (JP) 1994-07-20 EP disclosed
US-5258135-A Multiplexed displays, supertwisted birefringence effect CHISSO CORPORATION (JP) 1993-11-02 US disclosed
EP-0432780-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAID COMPOSITION CHISSO CORPORATION (JP) 1993-07-21 EP disclosed
US-5102577-A Supertwisted birefringence system CHISSO CORPORATION (JP) 1992-04-07 US disclosed
EP-0432780-A1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1991-06-19 EP disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed