Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4996905 | 1.00 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL237448 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL27497381 | 0.90 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL8095527 | 0.89 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL27087996 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL27087993 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL10803326 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL692514 | 0.86 | ALDH1A1 (0.61) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL31457255 | 0.85 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRTDP1MAPT | |
| SCHEMBL8094431 | 0.85 | SKP2 (0.43) | ALDH1A1CYP3A4TSHRTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371916-B1 | Curable casting resins based on polyurethane, and amine curing agent for these resins | CIBA GEIGY AG (CH) | 1994-07-27 | — | — | EP | claimed |
| EP-0371916-A2 | Curable casting resins based on polyurethane, and amine curing agent for these resins | CIBA-GEIGY AG (CH) | 1990-06-06 | — | — | EP | claimed |