Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24104500 | 1.00 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL26386510 | 1.00 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL30608221 | 1.00 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL24104493 | 1.00 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL26386513 | 1.00 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL26386460 | 0.86 | PDK1 (0.42) | L3MBTL1KMT2ASIGMAR1 | |
| SCHEMBL24105156 | 0.86 | PDK1 (0.42) | L3MBTL1KMT2ASIGMAR1 | |
| SCHEMBL26386458 | 0.86 | PDK1 (0.42) | L3MBTL1KMT2ASIGMAR1 | |
| SCHEMBL26386456 | 0.86 | PDK1 (0.42) | L3MBTL1KMT2ASIGMAR1 | |
| SCHEMBL26386569 | 0.86 | PDK1 (0.42) | L3MBTL1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5284855-A | Broad-spectrum antibiotics; gramnegative and -positive bacteria, esp. Enterobacter | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-08 | — | — | US | disclosed |
| US-5202337-A | Antibacterial agent, feed additive | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |
| US-5177210-A | Preparation of 2,7-diazabicyclo(3.3.0)octanes | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-05 | — | — | US | disclosed |
| US-5071999-A | Preparation of 2,7-diazabicyclo[3.3.0]octanes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |