SCHEMBL9344822

SCHEMBL9344822

C=CC(OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 2/20 0.33
USP2 O75604 1/20 0.33
TSHR P16473 1/20 0.33
S1PR4 O95977 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
S1PR1 P21453 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31
HDAC11 Q96DB2 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6712516 0.88 THRB (0.36) LMNAHDAC3HDAC4HDAC1HDAC7
SCHEMBL29029202 0.73 ELANE (0.42) L3MBTL1HTTMAPTALDH1A1LMNA
SCHEMBL2886387 0.70 CYP2C19 (0.43) L3MBTL1ALDH1A1LMNAHDAC3HDAC4
SCHEMBL2886386 0.70 CYP2C19 (0.43) L3MBTL1MAPTALDH1A1LMNAHDAC8
SCHEMBL13096918 0.70 TSHR (0.35) L3MBTL1HTTMAPTUSP2TSHR
SCHEMBL13096920 0.70 TSHR (0.35) L3MBTL1HTTMAPTUSP2TSHR
SCHEMBL9344820 0.69 L3MBTL1 (0.38) L3MBTL1HTTMAPTUSP2TSHR
SCHEMBL61038 0.68 CYP3A4 (0.50) MAPTUSP2TSHRALDH1A1LMNA
SCHEMBL11216512 0.68 CYP2D6 (0.42) L3MBTL1TSHRALDH1A1LMNACYP2C19
SCHEMBL299987 0.68 THRB (0.41) L3MBTL1ALDH1A1LMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0284081-B1 Silver halide photographic material FUJI PHOTO FILM CO LTD (JP) 1994-08-10 EP disclosed
US-4946771-A POLYMERIC COUPLERS; SHARPNESS, PREVENT MIXING OF COLORS FUJI PHOTO FILM CO., LTD. (JP) 1990-08-07 US disclosed
EP-0284081-A2 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-09-28 EP disclosed
US-4495275-A ANTISTATIC, ANTISTICKING AGENTS;WATER-SOLUBLE OPLYMERS WITH STYRENE MONOMER HAVING A FLUORINE-CONTAINING GROUP FUJI PHOTO FILM CO., LTD. (JP) 1985-01-22 US disclosed
US-4366238-A FLUORINE CONTAINING WATER INSOLUB STYRENIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1982-12-28 US disclosed