SCHEMBL686673

SCHEMBL686673

ClCCCCCCC(Cl)C(Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10395460 1.00 ALDH1A1 (0.36) ALDH1A1TSHRTDP1
SCHEMBL28832888 1.00 ALDH1A1 (0.36) ALDH1A1TSHRTDP1
SCHEMBL8465037 0.97 ALDH1A1 (0.35) ALDH1A1TSHRTDP1
SCHEMBL4960768 0.88
SCHEMBL9344838 0.88 TSHR (0.40) ALDH1A1TSHRTDP1
SCHEMBL29109626 0.85 ALDH1A1 (0.38) ALDH1A1TSHRTDP1
SCHEMBL28424132 0.83 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL28493937 0.83 ALDH1A1 (0.33) ALDH1A1TSHRTDP1
SCHEMBL25416010 0.81 ALDH1A1 (0.32) ALDH1A1TSHR
SCHEMBL22634847 0.81 ALDH1A1 (0.32) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669641-A Preparation method of alpha-lipoic acid 裴俊 2016-06-15 CN claimed
CN-109843939-B Polyolefin with low ash content and method for preparing same 格雷斯公司 2024-04-26 CN disclosed
EP-3074429-B1 PRODUCING PROPYLENE IMPACT COPOLYMERS AND PRODUCTS GRACE W R & CO (US) 2024-01-24 EP disclosed
EP-3837290-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2023-05-10 EP disclosed
US-11591458-B2 Polyolefins with low ash content and method of making same W.R. GRACE & CO.-CONN. (US) 2023-02-28 US disclosed
CN-115160459-A Catalyst systems for producing polyolefins and methods of making and using the same 格雷斯公司 2022-10-11 CN disclosed
CN-110023351-B Main catalyst composition prepared by combining internal electron donors 格雷斯公司 2022-04-26 CN disclosed
US-11236222-B2 Catalyst system for the production of polyolefins and method of making and using same W.R. GRACE & CO.-CONN. (US) 2022-02-01 US disclosed
US-11220519-B2 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-01-11 US disclosed
CN-112437780-B Components and catalysts for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2021-11-05 CN disclosed
US-5962361-A POLYMERIZATION CATALYST CONTAINING TITANIUM, MAGNESIUM UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-10-05 US disclosed
CN-1078161-A Fire-extinguishing composite LJUBERETSKOE N PROIZV OB SOJUZ (RU) 1993-11-10 CN disclosed
US-5229342-A Complex SHELL OIL COMPANY (US) 1993-07-20 US disclosed
US-5151399-A Magnesium, a titanium tetraalkoxide, a alkyl borate ester and an alkanol SHELL OIL COMPANY (US) 1992-09-29 US disclosed
US-5146028-A Selective catalyst, high bulk density polymer SHELL OIL COMPANY (US) 1992-09-08 US disclosed
US-5132263-A Polymerization catalysts of magnesium alkoxide, titanium tetraalkoxide and phenolic compounds as coordination catalysts SHELL OIL COMPANY (US) 1992-07-21 US disclosed
US-5124298-A Procatalyst of magnesium alkoxide, titanium tetraalkoxide, titanium halide, and phenolic compound; cocatalyst; selectivity control agent SHELL OIL COMPANY (US) 1992-06-23 US disclosed
US-5106806-A Precursor solution containing complex magnesium and titanium alkoxide, phenolic compound SHELL OIL COMPANY (US) 1992-04-21 US disclosed
US-5077357-A Titanium procatalyst and organoaluminum cocatalyst SHELL OIL COMPANY (US) 1991-12-31 US disclosed
US-5066737-A Complex Titanium-Magnesium Procatalyst, Organoaluminum Cocatalyst And A Selectivity Control Agent SHELL OIL COMPANY (US) 1991-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11220519-B2 Components and catalysts for the polymerization of olefins COG4, SCO2, COG2 ALDH1A1 3106/4885TSHR 2535/4885TDP1 3593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.