Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 12/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358276 | 0.85 | KIF11 (0.46) | CYP2D6CYP1A2KIF11DNMT1 | |
| SCHEMBL27911897 | 0.81 | CYP1A2 (0.42) | CYP2D6CYP1A2MAPTKMT2AKIF11 | |
| SCHEMBL11325383 | 0.79 | MAPT (0.47) | CYP2D6CYP1A2MAPTKMT2AEPHX1 | |
| SCHEMBL28299889 | 0.77 | KIF11 (0.43) | CYP2D6CYP1A2MAPTKMT2AKIF11 | |
| SCHEMBL1507933 | 0.76 | KCNN4 (0.54) | EPHX1KIF11 | |
| SCHEMBL2772327 | 0.75 | KIF11 (0.48) | CYP2D6CYP1A2KIF11DNMT1 | |
| SCHEMBL2772329 | 0.75 | KIF11 (0.48) | CYP2D6CYP1A2KIF11DNMT1 | |
| SCHEMBL13250261 | 0.75 | KIF11 (0.48) | CYP2D6CYP1A2KIF11DNMT1 | |
| SCHEMBL11258582 | 0.75 | MME (0.44) | LMNA | |
| SCHEMBL4840669 | 0.74 | KIF11 (0.43) | CYP2D6CYP1A2KIF11DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432014-B | Amido sulfur alcohol compound and preparation method thereof and its application in radiation protection | 中国医学科学院放射医学研究所 | 2019-08-16 | — | — | CN | disclosed |
| CN-106432014-A | Aminothiol compound, preparation method of aminothiol compound and application of aminothiol compound in radiation protection | 中国医学科学院放射医学研究所 | 2017-02-22 | — | — | CN | disclosed |
| EP-3060046-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | Dow AgroSciences LLC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-3060047-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | Dow AgroSciences, LLC (US) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015061157-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015061161-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2015-04-30 | — | — | WO | disclosed |
| US-8765817-B1 | Selective inhibitors of EG5 motors and methods of use | ARROWHEAD CENTER, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8349899-B1 | Selective inhibitors of EG5 motors and methods of use | ARROWHEAD CENTER, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| WO-2011008985-A2 | METHODS AND COMPOSITIONS FOR IMPROVED DELIVERY OF THERAPEUTIC AND DIAGNOSTIC AGENTS | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-20 | — | — | WO | disclosed |
| EP-1988896-A2 | IMMUNE RESPONSE MODIFIER CONJUGATES | 3M Innovative Properties Company (US) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007100634-A2 | IMMUNE RESPONSE MODIFIER CONJUGATES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-09-07 | — | — | WO | disclosed |