SCHEMBL358276

SCHEMBL358276

CC(SC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 18/20 0.46
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
DNMT1 P26358 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27911897 0.85 CYP1A2 (0.42) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL934496 0.85 CYP2D6 (0.46) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL28040180 0.84 KIF11 (0.38) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL11258582 0.81 MME (0.44)
SCHEMBL31091500 0.81 KIF11 (0.43) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL4840669 0.81 KIF11 (0.43) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL2772327 0.78 KIF11 (0.48) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL13250261 0.78 KIF11 (0.48) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL2772329 0.78 KIF11 (0.48) KIF11CYP1A2CYP2D6DNMT1
SCHEMBL1233527 0.78 KIF11 (0.42) KIF11CYP1A2CYP2D6DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS GIVAUDAN SA (CH) 2026-04-16 US disclosed
US-12570755-B2 Anti-CD20 antibody and uses thereof MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-03-10 US disclosed
US-12528801-B2 Substituted azacyles as TRPM8 modulators GIVAUDAN SA (CH) 2026-01-20 US disclosed
US-12522664-B2 Anti-CD20 antibody and uses thereof MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2026-01-13 US disclosed
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2025-09-25 US disclosed
CN-114555594-B Substituted azacycles as TRMP modulators 奇华顿股份有限公司 2025-03-18 CN disclosed
US-20240350655-A1 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS FORSCHUNGSVERBUND BERLIN E.V. (DE) 2024-10-24 US disclosed
CN-117946209-A Tumor targeting molecular probe and preparation method and application thereof 江西中医药大学 2024-04-30 CN disclosed
US-20240132487-A1 SUBSTITUTED AZACYLES AS TRMP8 MODULATORS GIVAUDAN SA (CH) 2024-04-25 US disclosed
US-20240124601-A1 ANTI-CD20 ANTIBODY AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER 2024-04-18 US disclosed
EP-1572645-A2 DERIVATIVES OF SUCCINIC AND GLUTARIC ACIDS AND ANALOGS THEREOF USEFUL AS INHIBITORS OF PHEX Enobia Pharma Inc. (CA) 2005-09-14 EP disclosed
US-20040186301-A1 Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex BIOMEP INC. 2004-09-23 US disclosed
WO-2004050620-A2 DERIVATIVES OF SUCCINIC AND GLUTARIC ACIDS AND ANALOGS THEREOF USEFUL AS INHIBITORS OF PHEX ENOBIA PHARMA (CA) 2004-06-17 WO disclosed
US-20030144260-A1 Heterocyclic compounds, method of developing new drug leads and combinatorial libraries used in such method YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2003-07-31 US disclosed
EP-1025118-A1 SPACER PEPTIDES AND MEMBRANES CONTAINING SAME MERCK PATENT GmbH (DE) 2000-08-09 EP disclosed
WO-1999020649-A1 SPACER PEPTIDES AND MEMBRANES CONTAINING SAME MERCK PATENT GMBH (DE) 1999-04-29 WO disclosed
US-5011975-A Novel (trans 1-propenyl)disulfide derivative and process for preparing the same NIPPON MIKTRON LIMITED (JP) 1991-04-30 US disclosed
EP-0013261-B1 GUAIACOL ESTERS OF ALPHA- AND BETA-MERCAPTOPROPIONYLALANINE AND ALPHA- AND BETA-MERCAPTOPROPIONYLGLYCINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1982-12-01 EP disclosed
US-4299842-A TREATMENT OF RESPIRATORY SYSTEM DISORDERS, NUCOLYTIC AGENTS CAVAZZA CLAUDIO 1981-11-10 US disclosed
EP-0013261-A1 Guaiacol esters of alpha- and beta-mercaptopropionylalanine and alpha- and beta-mercaptopropionylglycine, process for their preparation and pharmaceutical compositions containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1980-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260103459-A1 SUBSTITUTED AZACYLES AS TRPM8 MODULATORS TRPM8, TRPM7, TRPM5 KIF11 3328/4885CYP1A2 1434/4885CYP2D6 1572/4885
US-20240350655-A1 THIOL-CONJUGATION WITH UNSATURATED PHOSPHORUS(V) COMPOUNDS PTMS, PHOSPHO1, TYMP KIF11 3789/4885CYP1A2 4809/4885CYP2D6 4170/4885
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP KIF11 4388/4885CYP1A2 4816/4885CYP2D6 4642/4885
US-20240132487-A1 SUBSTITUTED AZACYLES AS TRMP8 MODULATORS TRPM8, TRPM7, TRPM5 KIF11 3494/4885CYP1A2 968/4885CYP2D6 2096/4885
US-12570755-B2 Anti-CD20 antibody and uses thereof CD209, BCL9, BCR KIF11 2895/4885CYP1A2 4089/4885CYP2D6 3970/4885
US-20040186301-A1 Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex GLS, SUCNR1, PGD KIF11 4807/4885CYP1A2 1550/4885CYP2D6 1525/4885
US-12528801-B2 Substituted azacyles as TRPM8 modulators TRPM8, TRPM7, TRPM4 KIF11 3692/4885CYP1A2 1702/4885CYP2D6 1935/4885
US-20030144260-A1 Heterocyclic compounds, method of developing new drug leads and combinatorial libraries used in such method AADAC, ABCG2, HDAC3 KIF11 3317/4885CYP1A2 718/4885CYP2D6 409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.