SCHEMBL934500

SCHEMBL934500

CC[Si](CC)(CC)CCOCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21749921 0.76
SCHEMBL7737993 0.74
SCHEMBL7737998 0.74 ALDH1A1 (0.32)
SCHEMBL5579 0.72
SCHEMBL11702185 0.72 TSHR (0.48)
Hydrochloric Acid SCHEMBL1958678 0.70
SCHEMBL4851320 0.69
SCHEMBL7399126 0.69
SCHEMBL28773506 0.69
SCHEMBL28792480 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101039949-B Method of producing silylalkoxymethyl halide DOW CORNING TORAY CO LTD 2015-05-06 CN disclosed
EP-1799694-B1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE DOW CORNING TORAY CO LTD (JP) 2012-05-09 EP disclosed
WO-2011154871-A1 HEPATITIS C VIRUS INHIBITORS PFIZER LIMITED (GB) 2011-12-15 WO disclosed
US-20110112100-A1 Hepatitis C Virus Inhibitors PFIZER INC. 2011-05-12 US disclosed
US-7915439-B2 Method of producing silylalkoxymethyl halide DOW CORNING TORAY COMPANY, LTD. (JP) 2011-03-29 US disclosed
WO-2011004276-A1 HEPATITIS C VIRUS INHIBITORS PFIZER LIMITED (GB) 2011-01-13 WO disclosed
US-20090203932-A1 Method of Producing Silylalkoxymethyl Halide DOW CORNING TORAY CO., LTD. (JP) 2009-08-13 US disclosed
US-7439232-B2 Heteroaryl 5-thio-β-D-glucopyranoside derivatives and therapeutic agents for diabetes containing the same TAISHO PHARMACEUTICAL CO., LTD. (JP) 2008-10-21 US disclosed
CN-101039949-A Method of producing silylalkoxymethyl halide DOW CORNING TORAY CO LTD (JP) 2007-09-19 CN disclosed
EP-1799694-A1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE Dow Corning Toray Co., Ltd. (JP) 2007-06-27 EP disclosed
US-20060194809-A1 Heteroaryl 5-thio-beta-d-gucopyranoside derivatives and therapeutic agents for diabetes containing the same TAISHO PHARMACEUTICAL CO., LTD. (JP) 2006-08-31 US disclosed
WO-2006040964-A1 METHOD OF PRODUCING SILYLALKOXYMETHYL HALIDE DOW CORNING TORAY CO., LTD. (JP) 2006-04-20 WO disclosed
EP-1609799-A1 HETEROARYL 5-THIO-BETA-D-GLUCOPYRANOSIDE DERIVATIVES AND REMEDIES FOR DIABETES CONTAINING THE SAME TAISHO PHARMACEUTICAL CO., LTD (JP) 2005-12-28 EP disclosed