Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048520 | 0.92 | MAPT (0.32) | HTTKMT2ALMNAPKML3MBTL1 | |
| SCHEMBL9046199 | 0.90 | ELANE (0.36) | HTTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9045154 | 0.90 | MAPT (0.33) | HTTALDH1A1KMT2ALMNAL3MBTL1 | |
| SCHEMBL9341477 | 0.88 | YTHDC1 (0.38) | ALDH1A1LMNA | |
| SCHEMBL9776194 | 0.84 | NPC1 (0.38) | CNOT7HTTALDH1A1KMT2AP2RX3 | |
| SCHEMBL9776204 | 0.82 | MEN1 (0.42) | HTTKMT2ALMNACASRKDM4E | |
| SCHEMBL9045926 | 0.77 | YTHDC1 (0.45) | ALDH1A1LMNA | |
| SCHEMBL9776056 | 0.76 | NPC1 (0.31) | ALDH1A1KMT2APKMKDM4E | |
| SCHEMBL9045074 | 0.76 | ELANE (0.33) | ALDH1A1ELANE | |
| SCHEMBL9046159 | 0.76 | ELANE (0.33) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344932-A | N-(pyrrolo(2,3-d)pyrimidin-3-ylacyl)-glutamic acid derivatives | TRUSTEES OF PRINCETON UNIVERSITY (US) | 1994-09-06 | — | — | US | disclosed |