Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344811 | 0.90 | MEN1 (0.69) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9343960 | 0.85 | MEN1 (0.52) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9345173 | 0.83 | KMT2A (0.40) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL794085 | 0.77 | MEN1 (0.73) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL1430608 | 0.77 | MEN1 (0.73) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9345165 | 0.77 | MEN1 (0.53) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9343957 | 0.77 | MEN1 (0.53) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9344792 | 0.76 | GRIN2D (0.46) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL9345597 | 0.74 | MEN1 (0.50) | MEN1ALOX15CYP2C19KMT2AHSD17B10 | |
| SCHEMBL5096121 | 0.74 | SLC6A4 (0.57) | ALOX15CYP2C19TDP1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321016-A | Epliepsy, central nervous system disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1994-06-14 | — | — | US | disclosed |
| US-5162311-A | Treating epilepsy, psychiatric disorders | SANDOZ PHARMACEUTICALS CORP. (US) | 1992-11-10 | — | — | US | disclosed |