Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345162 | 1.00 | ELANE (0.46) | ELANENPC1CA12CA1CA2 | |
| SCHEMBL9345266 | 0.84 | NPC1 (0.47) | ELANENPC1CA12CA1CA2 | |
| SCHEMBL9344775 | 0.84 | NPC1 (0.47) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL17264967 | 0.82 | NPC1 (0.46) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL9349689 | 0.82 | S100B (0.43) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL9349681 | 0.82 | S100B (0.43) | NPC1CA12CA1CA2CA9 | |
| SCHEMBL9344732 | 0.81 | ELANE (0.47) | ELANENPC1CA12CA1CA2 | |
| SCHEMBL17264966 | 0.81 | LMNA (0.50) | NPC1TSHRKMT2AMEN1RAB9A | |
| SCHEMBL28550850 | 0.81 | NPC1 (0.44) | ELANENPC1CA1CA2RAB9A | |
| SCHEMBL28559769 | 0.81 | NPC1 (0.44) | ELANENPC1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457334-B1 | Carbonates of acetylenic alcohols | NIPPON PAINT CO LTD (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5258542-A | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| US-5194653-A | Useful in making heat resistant liquid crystalline polymers | NIPPON PAINT COMPANY, LIMITED (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0457334-A1 | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |