⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654997 | 0.78 | — | — | |
| SCHEMBL4751006 | 0.78 | — | — | |
| SCHEMBL11510129 | 0.67 | — | — | |
| SCHEMBL367523 | 0.58 | EGFR (0.32) | — | |
| SCHEMBL6235782 | 0.57 | — | — | |
| SCHEMBL3279288 | 0.56 | EGFR (0.34) | — | |
| SCHEMBL4957462 | 0.56 | METAP2 (0.44) | — | |
| SCHEMBL13175052 | 0.56 | NR3C1 (0.44) | — | |
| SCHEMBL1193887 | 0.56 | METAP2 (0.44) | — | |
| SCHEMBL10857663 | 0.56 | METAP2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0341065-B1 | Immunostimulating guanine dervatives, compositions and methods | SCRIPPS CLINIC RES (US) | 1994-07-27 | — | — | EP | disclosed |
| US-5136030-A | Immunostimulating guanine derivatives, compositions and methods | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5011828-A | Immunostimulating guanine derivatives, compositions and methods | SCRIPPS CLINIC AND RESEARCH FOUNDATION | 1991-04-30 | — | — | US | disclosed |
| EP-0341065-A2 | Immunostimulating guanine dervatives, compositions and methods | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-11-08 | — | — | EP | disclosed |