SCHEMBL9345374

SCHEMBL9345374

CC(C)(C)C(O[SiH](c1ccccc1)c1ccccc1)[C@@H]1C[C@H](O)CCO1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.31
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9343521 1.00 SLC6A3 (0.31) SLC6A3CHRM3
SCHEMBL9343516 1.00 SLC6A3 (0.31) SLC6A3CHRM3
SCHEMBL8825512 0.82 SLC6A3 (0.39) SLC6A3
SCHEMBL8825521 0.82 SLC6A3 (0.39) SLC6A3
SCHEMBL9266679 0.78
SCHEMBL9274172 0.78
SCHEMBL3969000 0.77 MMP1 (0.33) SLC6A3
SCHEMBL7865233 0.76
SCHEMBL20447643 0.75 NPY1R (0.33) SLC6A3
SCHEMBL4083454 0.74 SLC18A3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0604483-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES ZENECA LIMITED (GB) 1994-07-06 EP claimed
WO-1993006235-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES ZENECA LIMITED (GB) 1993-04-01 WO claimed
EP-0604483-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES ZENECA LIMITED (GB) 1994-07-06 EP disclosed
WO-1993006235-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE 4-HYDROXYTETRAHYDRO-2-PYRANONE DERIVATIVES ZENECA LIMITED (GB) 1993-04-01 WO disclosed