Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934545 | 0.78 | MME (0.48) | MMESLC1A3SLC1A2SLC1A1DPP4 | |
| Oxalic Acid SCHEMBL9434079 | 0.77 | SLC1A3 (0.48) | MMESLC1A3SLC1A2SLC1A1TAS1R3 | |
| SCHEMBL2846532 | 0.77 | CYP1A2 (0.55) | SLC1A3SLC1A2SLC1A1CYP1A2FOLH1 | |
| SCHEMBL3662060 | 0.77 | CYP1A2 (0.55) | SLC1A3SLC1A2SLC1A1CYP1A2FOLH1 | |
| SCHEMBL4692054 | 0.76 | ESR1 (0.53) | TAAR1CA1CA2 | |
| SCHEMBL17449974 | 0.75 | DPP4 (0.48) | MMESLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL5257074 | 0.75 | DPP4 (0.48) | MMESLC1A3SLC1A2SLC1A1DPP4 | |
| SCHEMBL9325429 | 0.75 | DRD2 (0.43) | MMESLC1A3SLC1A2SLC1A1TAS1R3 | |
| SCHEMBL15915088 | 0.74 | LMNA (0.48) | CYP1A2CYP2C9CYP2C19CA1CA2 | |
| SCHEMBL27821288 | 0.74 | CSNK1E (0.40) | MMESLC1A3SLC1A2SLC1A1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |