Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344775 | 0.84 | NPC1 (0.47) | GSTP1NPC1MEN1KMT2AMAOA | |
| SCHEMBL9344536 | 0.78 | NPC1 (0.50) | LMNANPC1MEN1KMT2AMAOA | |
| SCHEMBL28560297 | 0.78 | NPC1 (0.50) | NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL28559769 | 0.78 | NPC1 (0.44) | NPC1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL9344441 | 0.77 | NPC1 (0.39) | GSTP1NPC1MAOAMAOB | |
| SCHEMBL9345266 | 0.74 | NPC1 (0.47) | GSTP1NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL9349409 | 0.73 | ATM (0.41) | GSTP1NPC1S1PR1S1PR5MAOA | |
| SCHEMBL17264967 | 0.73 | NPC1 (0.46) | NPC1KMT2AMAOBFAAHATM | |
| SCHEMBL7571353 | 0.72 | CYP1A2 (0.46) | ALDH1A1 | |
| SCHEMBL17022741 | 0.72 | NPC1 (0.47) | LMNAGSTP1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258542-A | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1993-11-02 | — | — | US | claimed |
| EP-0457334-B1 | Carbonates of acetylenic alcohols | NIPPON PAINT CO LTD (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5258542-A | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| US-5194653-A | Useful in making heat resistant liquid crystalline polymers | NIPPON PAINT COMPANY, LIMITED (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0457334-A1 | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |