SCHEMBL7571353

SCHEMBL7571353

CCOC(=O)Oc1ccc(-c2ccccc2)cc1Cl

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
RAB9A P51151 1/20 0.46
CUL4A Q13619 1/20 0.45
ESR2 Q92731 1/20 0.42
ALOX5 P09917 2/20 0.42
PTGES O14684 1/20 0.42
TARBP2 Q15633 1/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
KDM4E B2RXH2 1/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
DHODH Q02127 1/20 0.41
SLC6A9 P48067 1/20 0.41
HPGD P15428 1/20 0.41
XBP1 P17861 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7571401 0.85 PPARG (0.52) ALOX5TARBP2ALDH1A1MAPTPPARG
SCHEMBL7095207 0.82 CUL4A (0.46) CYP1A2RAB9ACUL4AALOX5ALDH1A1
SCHEMBL7578265 0.81 ALOX5 (0.48) ALOX5TARBP2PPARGPPARADHODH
SCHEMBL5706075 0.80 MAPT (0.47) RAB9ACUL4AALDH1A1MAPTNPSR1
SCHEMBL6222370 0.78 ALPL (0.43) CYP1A2CUL4AALOX5PTGESTARBP2
SCHEMBL31047106 0.78 CUL4A (0.48) CYP1A2RAB9ACUL4AALDH1A1CYP2C19
SCHEMBL810361 0.78 CUL4A (0.48) CYP1A2RAB9ACUL4AALDH1A1CYP2C19
SCHEMBL6976915 0.77 NPC1 (0.51) CYP1A2RAB9AALOX5TARBP2ALDH1A1
SCHEMBL5059050 0.77 TSHR (0.54) CYP1A2RAB9AALDH1A1MAPTNPSR1
SCHEMBL1666002 0.75 ALDH1A1 (0.47) CUL4AALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes BAYER AKTIENGESELLSCHAFT (DE) 2002-07-04 US disclosed
US-6410581-B1 INSECTICIDES, MITICIDES, NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086892-A1 For controlling animal pests, in particular: insects, arachnids and nematodes ATXN2, HAX1, ANTXR2 CYP1A2 89/4885RAB9A 1115/4885CUL4A 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.