Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559370 | 0.81 | NPC1 (0.49) | NPC1PPARGTSHRL3MBTL1 | |
| SCHEMBL9345499 | 0.77 | LMNA (0.36) | NPC1GSTP1MAOAMAOB | |
| SCHEMBL7571401 | 0.76 | PPARG (0.52) | PPARGPPARAMRGPRX4 | |
| SCHEMBL9344775 | 0.75 | NPC1 (0.47) | NPC1GSTP1TSHRCA12CA1 | |
| SCHEMBL6222370 | 0.75 | ALPL (0.43) | PPARGPPARATSHR | |
| SCHEMBL9817942 | 0.74 | NPC1 (0.37) | NPC1PPARGGSTP1TSHR | |
| SCHEMBL21790496 | 0.73 | PPARG (0.46) | PPARGPPARAMRGPRX4CFD | |
| SCHEMBL21790495 | 0.73 | PPARG (0.46) | PPARGPPARAMRGPRX4CFD | |
| SCHEMBL17355750 | 0.73 | MAOA (0.42) | NPC1TSHRMAOAMAOBL3MBTL1 | |
| SCHEMBL28559758 | 0.73 | CA12 (0.46) | NPC1TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258542-A | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1993-11-02 | — | — | US | claimed |
| EP-0457334-B1 | Carbonates of acetylenic alcohols | NIPPON PAINT CO LTD (JP) | 1994-08-10 | — | — | EP | disclosed |
| US-5258542-A | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1993-11-02 | — | — | US | disclosed |
| US-5194653-A | Useful in making heat resistant liquid crystalline polymers | NIPPON PAINT COMPANY, LIMITED (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0457334-A1 | Carbonates of acetylenic alcohols | NIPPON PAINT CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |