Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178208 | 0.97 | CYP4F2 (0.51) | CYP4F2CYP4A11TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL9348474 | 0.92 | TSHR (0.50) | CYP4F2CYP4A11TSHRSMN1; SMN2CYP19A1 | |
| SCHEMBL11772453 | 0.83 | NPC1 (0.53) | TSHRSMN1; SMN2TDP1CA12CA1 | |
| Ethyl Salicylate SCHEMBL29113780 | 0.83 | TSHR (0.57) | CYP4F2CYP4A11TSHRCYP3A4TDP1 | |
| SCHEMBL28237669 | 0.83 | CYP4F2 (0.52) | CYP4F2CYP4A11TSHRCYP1A2SMN1; SMN2 | |
| Ethyl Salicylate SCHEMBL8780941 | 0.82 | TSHR (0.56) | CYP4F2CYP4A11TSHRCYP3A4TDP1 | |
| SCHEMBL9730413 | 0.82 | HNF4A (0.51) | CYP4F2CYP4A11CYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL14925380 | 0.81 | HTT (0.68) | TSHRSMN1; SMN2CYP3A4CA12CA1 | |
| SCHEMBL9348517 | 0.81 | HDAC8 (0.59) | CYP4F2CYP4A11TSHRABCB1ALDH1A1 | |
| SCHEMBL5341547 | 0.81 | HTT (0.57) | SMN1; SMN2CYP19A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292768-A | Compound effective as cerebral insufficiency improver | SUNTORY LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |