Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329969 | 0.95 | SSTR4 (0.57) | SSTR4SSTR1 | |
| SCHEMBL21748734 | 0.86 | SSTR4 (0.54) | SSTR4SSTR1 | |
| SCHEMBL21748736 | 0.86 | SSTR4 (0.54) | SSTR4SSTR1 | |
| SCHEMBL5839921 | 0.78 | PDK1 (0.42) | SSTR4SSTR1 | |
| SCHEMBL620243 | 0.78 | PDK1 (0.58) | — | |
| SCHEMBL12612604 | 0.78 | ALDH1A1 (0.64) | SSTR4SSTR1 | |
| SCHEMBL9345695 | 0.77 | SSTR4 (0.62) | SSTR4SSTR1 | |
| SCHEMBL18389997 | 0.76 | SSTR4 (0.50) | SSTR4SSTR1 | |
| SCHEMBL31745106 | 0.76 | SSTR4 (0.54) | SSTR4SSTR1 | |
| SCHEMBL8314042 | 0.75 | PDK1 (0.42) | SSTR4SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5280031-A | Cyclic azaaliphatic compounds with a nitroxy function, processes for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-01-18 | — | — | US | disclosed |
| US-5030641-A | Treatment of angina pectoris, hypotensive agents | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-09 | — | — | US | disclosed |