Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9447841 | 0.79 | ALDH1A1 (0.36) | ALDH1A1LMNASTSNPC1RAB9A | |
| SCHEMBL9350090 | 0.69 | STS (0.36) | ALDH1A1LMNASTSNPC1RAB9A | |
| SCHEMBL9345782 | 0.68 | — | — | |
| SCHEMBL9441400 | 0.60 | BCHE (0.40) | ALDH1A1NPC1RAB9ASMN1; SMN2EPHX2 | |
| SCHEMBL13503970 | 0.57 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL14223754 | 0.56 | HRH3 (0.41) | ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL1822033 | 0.56 | MAOB (0.47) | SLC6A4SLC6A3 | |
| SCHEMBL31304814 | 0.56 | TSHR (0.47) | ALDH1A1SLC6A4SLC6A3 | |
| SCHEMBL1824702 | 0.55 | MAOB (0.55) | ALDH1A1SMN1; SMN2SLC6A4 | |
| SCHEMBL3365060 | 0.55 | LTA4H (0.51) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359054-A | Progesterone inhibitors | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-10-25 | — | — | US | disclosed |