Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972664 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL698685 | 0.79 | GAA (0.47) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL28357204 | 0.77 | GAA (0.49) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL16781055 | 0.74 | POLB (0.55) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL3902580 | 0.74 | GAA (0.46) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL23328032 | 0.72 | MKNK1 (0.41) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL27929951 | 0.72 | POLB (0.36) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL28877315 | 0.70 | CYP3A4 (0.46) | ALDH1A1POLBKMT2AMEN1GAA | |
| SCHEMBL18740829 | 0.70 | GAA (0.46) | ALDH1A1HPGDPOLBKMT2AMEN1 | |
| SCHEMBL7406703 | 0.69 | POLB (0.50) | ALDH1A1HPGDPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295017-B1 | Aromatic polyamides | MITSUI TOATSU CHEMICALS (JP) | 1994-08-17 | — | — | EP | claimed |
| US-4921933-A | FILMS, STORAGE MODULUS, GLASS TRANSITION TEMPERATURE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-05-01 | — | — | US | claimed |
| EP-0295017-A2 | Aromatic polyamides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-12-14 | — | — | EP | claimed |
| EP-0295017-B1 | Aromatic polyamides | MITSUI TOATSU CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-4921933-A | FILMS, STORAGE MODULUS, GLASS TRANSITION TEMPERATURE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1990-05-01 | — | — | US | disclosed |
| EP-0295017-A2 | Aromatic polyamides | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-12-14 | — | — | EP | disclosed |