Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902580 | 0.94 | GAA (0.46) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL18740829 | 0.91 | GAA (0.46) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL10832124 | 0.84 | PDE10A (0.50) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL28357204 | 0.82 | GAA (0.49) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9345855 | 0.79 | ALDH1A1 (0.43) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL17292696 | 0.79 | MEN1 (0.52) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27663766 | 0.78 | PDE10A (0.49) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12111485 | 0.78 | ALDH1A1 (0.58) | GAAMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL8030410 | 0.78 | LMNA (0.38) | GAAALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL27816594 | 0.78 | PDE10A (0.47) | GAAMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423176-A1 | CARBOXYLIC ACID COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-29 | — | — | EP | disclosed |