Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | CCR5 | P51681 | 2/20 | 0.63 |
| ▸ | ERCC1 | P07992 | 3/20 | 0.62 |
| ▸ | ERCC4 | Q92889 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | SELL | P14151 | 1/20 | 0.56 |
| ▸ | SELP | P16109 | 1/20 | 0.56 |
| ▸ | SELE | P16581 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108603 | 0.87 | ALOX15 (0.67) | MAPTALOX15CCR5ERCC1ERCC4 | |
| SCHEMBL23072662 | 0.87 | MAPT (0.62) | MAPTHTTALOX15CCR5GAA | |
| SCHEMBL14015912 | 0.84 | BCHE (0.72) | MAPTERCC1ERCC4GAASELP | |
| SCHEMBL12915848 | 0.82 | MAPT (0.80) | MAPTHTTGAALMNATRPV1 | |
| SCHEMBL2832908 | 0.81 | CCR5 (0.60) | ALOX15CCR5GAA | |
| SCHEMBL6105153 | 0.81 | HCAR2 (0.73) | SELPSELE | |
| SCHEMBL3061430 | 0.81 | MAPT (1.00) | MAPTHTTGAALMNA | |
| SCHEMBL2833387 | 0.80 | MEN1 (0.57) | MAPTALOX15CCR5GAALMNA | |
| SCHEMBL10711009 | 0.80 | MAPT (0.66) | MAPTHTTGAALMNATRPV1 | |
| SCHEMBL9444668 | 0.80 | ERCC1 (0.89) | MAPTERCC1ERCC4GAASELL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333522-B1 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5232923-A | Stimulates production of nerve growth factor; administering for treatment of regressive disorders of the central nervous system | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0333522-A2 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-20 | — | — | EP | disclosed |