SCHEMBL934622

SCHEMBL934622

C=CC(=O)CC(N)(N)C(=O)C=C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
FGFR4 P22455 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10777139 0.73
SCHEMBL9066622 0.73 ALDH1A1 (0.41) ALDH1A1TSHRFGFR4
SCHEMBL588499 0.71
SCHEMBL3394150 0.70 ALDH1A1 (0.37) ALDH1A1TSHRFGFR4
SCHEMBL4809291 0.67
SCHEMBL10042795 0.67 ALDH1A1 (0.50) ALDH1A1TSHRFGFR4
SCHEMBL11506422 0.67
SCHEMBL9344012 0.67
SCHEMBL9245591 0.67 ALDH1A1 (0.34) ALDH1A1TSHR
SCHEMBL1946986 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2454300-A1 PRODUCTION AND USE OF POLYMERS COMPRISING HYDROXY GROUPS AND ACRYLATE GROUPS BASF SE (DE) 2012-05-23 EP claimed
WO-2011006947-A1 PRODUCTION AND USE OF POLYMERS COMPRISING HYDROXY GROUPS AND ACRYLATE GROUPS BASF SE (DE) 2011-01-20 WO claimed
US-4593073-A Hydrophilic backbone bonded with a arginine or lysine compound THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARING (MCGILL UNIV.) (CA) 1986-06-03 US claimed
EP-0394318-A1 POLYMERS AND POLYMER-PEPTIDE CONJUGATES MEDICAL RESEARCH COUNCIL (GB) 1990-10-31 EP disclosed
WO-1989005305-A1 POLYMERS AND POLYMER-PEPTIDE CONJUGATES 3I RESEARCH EXPLOITATION LIMITED (GB) 1989-06-15 WO disclosed
US-4593073-A Hydrophilic backbone bonded with a arginine or lysine compound THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARING (MCGILL UNIV.) (CA) 1986-06-03 US disclosed