Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31376416 | 0.80 | ALDH1A1 (0.32) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL517353 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TSHRFGFR4LMNA | |
| SCHEMBL3578262 | 0.72 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2HIF1ATSHRFGFR4 | |
| SCHEMBL30895615 | 0.72 | SMN1; SMN2 (0.32) | ALDH1A1SMN1; SMN2HIF1ATSHRFGFR4 | |
| SCHEMBL28173843 | 0.70 | ALDH1A1 (0.38) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL1411891 | 0.70 | ALDH1A1 (0.38) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL9245591 | 0.70 | ALDH1A1 (0.34) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL21979219 | 0.70 | SMN1; SMN2 (0.31) | SMN1; SMN2HIF1ALMNA | |
| SCHEMBL12501681 | 0.70 | SMN1; SMN2 (0.31) | SMN1; SMN2HIF1ALMNA | |
| SCHEMBL934622 | 0.70 | ALDH1A1 (0.39) | ALDH1A1TSHRFGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212020-A1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | MIP Technologies AB (SE) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009064245-A1 | IMPRINTED POLYMERS WITH AFFINITY FOR PHOSPHORYLATED PEPTIDES AND PROTEINS | MIP TECHNOLOGIES AB (SE) | 2009-05-22 | — | — | WO | disclosed |