Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9347039 | 0.98 | CHRNA7 (0.40) | CHRNA7 | |
| SCHEMBL9342865 | 0.74 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL9150768 | 0.72 | CHRNA7 (0.42) | CHRNA7 | |
| SCHEMBL6840373 | 0.69 | — | — | |
| SCHEMBL19381888 | 0.69 | MAPK1 (0.36) | — | |
| SCHEMBL19773424 | 0.68 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL14212538 | 0.68 | OGA (0.49) | — | |
| SCHEMBL17864283 | 0.68 | NOS1 (0.36) | — | |
| SCHEMBL9343624 | 0.68 | CHRNA7 (0.41) | CHRNA7 | |
| SCHEMBL9342013 | 0.68 | CHRM2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307141-B1 | OXAZOLES AND THIAZOLES FOR THE TREATMENT OF SENILE DEMENTIA | MERCK SHARP & DOHME LTD. (GB) | 1993-01-13 | — | — | EP | claimed |
| EP-0307141-A2 | Oxazoles and thiazoles for the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | claimed |
| US-5324723-A | Analgesics | MERCK SHARPE & DOHME LTD. | 1994-06-28 | — | — | US | disclosed |
| EP-0307141-B1 | OXAZOLES AND THIAZOLES FOR THE TREATMENT OF SENILE DEMENTIA | MERCK SHARP & DOHME LTD. (GB) | 1993-01-13 | — | — | EP | disclosed |
| EP-0307141-A2 | Oxazoles and thiazoles for the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |