Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | PNP | P00491 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346424 | 1.00 | HIF1A (0.69) | HIF1APNPLMNATP53HTT | |
| SCHEMBL5982268 | 0.90 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| SCHEMBL5982275 | 0.90 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| Deoxyadenosine SCHEMBL5182039 | 0.86 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| Deoxyadenosine SCHEMBL532825 | 0.86 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| Deoxyadenosine SCHEMBL23982174 | 0.86 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| Deoxyadenosine SCHEMBL193181 | 0.86 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| Deoxyadenosine SCHEMBL21637036 | 0.86 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| Deoxyadenosine SCHEMBL593935 | 0.86 | HIF1A (0.71) | HIF1APNPLMNATP53HTT | |
| Deoxyadenosine SCHEMBL19877 | 0.86 | HIF1A (0.71) | HIF1APNPLMNATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | disclosed |
| US-5026836-A | Antitumor agents | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0353268-A4 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RES INST (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0353268-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RESEARCH INST (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989005817-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1989-06-29 | — | — | WO | disclosed |