SCHEMBL9346540

SCHEMBL9346540

CCCCCc1nnc(C)s1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.60
NPSR1 Q6W5P4 1/20 0.47
CYP2C9 P11712 1/20 0.46
POLB P06746 3/20 0.43
HRH2 P25021 1/20 0.42
HRH1 P35367 1/20 0.42
HRH4 Q9H3N8 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
AKT1 P31749 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.39
RAB9A P51151 2/20 0.38
HSD17B10 Q99714 2/20 0.38
DNMT1 P26358 1/20 0.38
MEN1 O00255 1/20 0.38
GAPDH P04406 1/20 0.38
ALOX15 P16050 1/20 0.38
NR4A1 P22736 1/20 0.38
APEX1 P27695 1/20 0.38
PTPN7 P35236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21276016 0.98 ALDH1A1 (0.63) ALDH1A1NPSR1CYP2C9POLBHRH2
SCHEMBL11422899 0.98 ALDH1A1 (0.63) ALDH1A1NPSR1CYP2C9POLBHRH2
SCHEMBL13419534 0.96 ALDH1A1 (0.53) ALDH1A1NPSR1CYP2C9POLBHRH2
SCHEMBL15042254 0.89 ALDH1A1 (0.54) ALDH1A1NPSR1CYP2C9POLBHRH2
SCHEMBL15042230 0.88 ALDH1A1 (0.52) ALDH1A1NPSR1CYP2C9POLBHRH2
SCHEMBL6406054 0.86 ALDH1A1 (0.69) ALDH1A1NPSR1CYP2C9POLBSMN1; SMN2
SCHEMBL13803975 0.84
SCHEMBL22368217 0.84 ALDH1A1 (0.73) ALDH1A1NPSR1CYP2C9POLBSMN1; SMN2
SCHEMBL6553986 0.84 ALDH1A1 (0.73) ALDH1A1NPSR1CYP2C9POLBSMN1; SMN2
SCHEMBL31244838 0.84 ALDH1A1 (0.73) ALDH1A1NPSR1CYP2C9POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019010165-A1 BENZAMIDE INHIBITORS OF BACTERICAL LIPOPROTEIN SIGNAL PEPTIDASE THE SCRIPPS RESEARCH INSTITUTE (US) 2019-01-10 WO disclosed
US-5336546-A Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 1994-08-09 US disclosed
EP-0548366-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-06-30 EP disclosed