Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | PYGB | P11216 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448246 | 0.99 | CA12 (0.44) | CA12CA1CA2CA9PYGB | |
| SCHEMBL28448523 | 0.99 | CA12 (0.44) | CA12CA1CA2CA9PYGB | |
| SCHEMBL28444663 | 0.99 | CA12 (0.44) | CA12CA1CA2CA9PYGB | |
| SCHEMBL734876 | 0.99 | CA12 (0.44) | CA12CA1CA2CA9PYGB | |
| SCHEMBL2723573 | 0.86 | PYGB (0.43) | CA12CA1CA2CA9PYGB | |
| SCHEMBL29240455 | 0.82 | FOLH1 (0.40) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL30259669 | 0.82 | FOLH1 (0.40) | CA12CA1CA2CA9FOLH1 | |
| SCHEMBL2354072 | 0.81 | PYGB (0.44) | CA12CA1CA2CA9PYGB | |
| SCHEMBL31206883 | 0.81 | PYGB (0.46) | CA12CA1CA2CA9PYGB | |
| SCHEMBL28135999 | 0.81 | PYGB (0.44) | CA12CA1CA2CA9PYGB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374712-A | A lysine and arginine residue crosslinked with a pentose sugar: pentosidine, a product in aging of proteins; useful in medical diagnosis | CASE WESTERN RESERVE UNIVERSITY (US) | 1994-12-20 | — | — | US | disclosed |