Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4984363 | 0.91 | KMT2A (0.62) | PKMMAPK1KDM4EL3MBTL1LMNA | |
| SCHEMBL4984380 | 0.87 | KMT2A (0.56) | PKMMAPK1KDM4EL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL29852570 | 0.86 | KMT2A (0.54) | PKMMAPK1KDM4EL3MBTL1LMNA | |
| SCHEMBL1584846 | 0.85 | PKM (0.52) | PKMMAPK1L3MBTL1LMNAKMT2A | |
| SCHEMBL1741858 | 0.84 | TDP1 (0.57) | PKMMAPK1KDM4EL3MBTL1LMNA | |
| SCHEMBL4989856 | 0.84 | P4HTM (0.61) | PKMMAPK1KDM4EL3MBTL1LMNA | |
| SCHEMBL22388846 | 0.82 | KMT2A (0.76) | PKMMAPK1KDM4ELMNAKMT2A | |
| SCHEMBL14186819 | 0.82 | LMNA (0.51) | PKMMAPK1KDM4EL3MBTL1LMNA | |
| SCHEMBL12612944 | 0.81 | POLB (0.57) | PKML3MBTL1LMNAKMT2ATDP1 | |
| SCHEMBL23397122 | 0.81 | LMNA (0.58) | PKMMAPK1L3MBTL1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364873-A | Influencing metabolism of collagen | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| US-5238948-A | Influence metabolism of collagen or biosynthesis of C1q | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |