Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL9347147

N.OB(F)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
KIF11 P52732 1/20 0.36
ALOX15 P16050 1/20 0.35
TRPV6 Q9H1D0 2/20 0.35
PTPN1 P18031 1/20 0.34
MAPK1 P28482 1/20 0.33
KCNN4 O15554 2/20 0.32
CYP2C19 P33261 2/20 0.32
HIF1A Q16665 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
ENPP2 Q13822 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1333551 0.98 ALDH1A1 (0.39) ALDH1A1TSHRKIF11ALOX15TRPV6
SCHEMBL9004518 0.96 ALDH1A1 (0.37) ALDH1A1TSHRKIF11ALOX15TRPV6
SCHEMBL723306 0.96 ALDH1A1 (0.37) ALDH1A1TSHRKIF11ALOX15TRPV6
Pyridine SCHEMBL6516960 0.85 TSHR (0.34) ALDH1A1TSHRKIF11TRPV6CYP2C19
SCHEMBL8182003 0.82 KIF11 (0.42) KIF11CA4ENPP2KCNH2
Ammonia Solution, Strong SCHEMBL2816571 0.80 KIF11 (0.38) ALDH1A1TSHRKIF11ALOX15TRPV6
Benzene SCHEMBL27568485 0.79 KIF11 (0.40) ALDH1A1TSHRKIF11ALOX15TRPV6
SCHEMBL723986 0.79 KIF11 (0.40) ALDH1A1TSHRKIF11ALOX15TRPV6
SCHEMBL28419769 0.79 KIF11 (0.40) ALDH1A1TSHRKIF11ALOX15TRPV6
SCHEMBL1333548 0.79 TSHR (0.42) ALDH1A1TSHRKIF11ALOX15TRPV6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5369195-A Flexibility SHELL OIL COMPANY (US) 1994-11-29 US disclosed