Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 8/20 | 0.61 |
| ▸ | EYA3 | Q99504 | 5/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 3/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2943743 | 0.91 | PTPN1 (0.67) | CYP2C9EYA3PTPN1TTRTHRB | |
| SCHEMBL4670709 | 0.87 | EYA3 (0.64) | CYP2C9EYA3PTPN1TTRSLC22A12 | |
| Hydrochloric Acid SCHEMBL9347221 | 0.84 | CYP2C9 (0.58) | CYP2C9EYA3PTPN1TTRSLC22A12 | |
| SCHEMBL28332728 | 0.82 | CYP2C9 (0.55) | CYP2C9EYA3PTPN1TTRSLC22A12 | |
| SCHEMBL11840583 | 0.80 | EYA3 (0.85) | CYP2C9EYA3PTPN1TTRSLC22A12 | |
| SCHEMBL11843283 | 0.79 | CYP2C9 (0.67) | CYP2C9EYA3PTPN1TTRSLC22A12 | |
| SCHEMBL27992957 | 0.78 | EYA3 (0.80) | EYA3PTPN1TTRTHRBTHRA | |
| SCHEMBL9605230 | 0.77 | EYA3 (0.43) | CYP2C9EYA3PTPN1TTRSLC22A12 | |
| SCHEMBL2944813 | 0.77 | PTPN1 (0.69) | EYA3PTPN1TTRTHRBTHRA | |
| Hydrochloric Acid SCHEMBL9347277 | 0.76 | PTPN1 (0.67) | EYA3PTPN1TTRTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338746-B1 | 2-Alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them | TARO PHARMA IND (IL) | 1994-08-31 | — | — | EP | disclosed |
| EP-0338746-A1 | 2-Alkyl-3-benzoylbenzofurans and pharmaceutical compositions containing them | Taro Pharmaceutical Industries Ltd. (IL) | 1989-10-25 | — | — | EP | disclosed |
| US-4831054-A | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia | TARO PHARMACEUTICALS, LTD. (IL) | 1989-05-16 | — | — | US | disclosed |