Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23043376 | 1.00 | FKBP1A (0.53) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL5965409 | 0.95 | FKBP1A (0.56) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL15406170 | 0.95 | FKBP1A (0.56) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL1472797 | 0.94 | FKBP1A (0.60) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL1472792 | 0.90 | FKBP1A (0.64) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL1472793 | 0.90 | FKBP1A (0.64) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL13248928 | 0.90 | FKBP1A (0.64) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL5458626 | 0.88 | CYP3A4 (0.54) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL5451605 | 0.88 | CYP3A4 (0.54) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A | |
| SCHEMBL9352245 | 0.88 | CYP3A4 (0.54) | FKBP1ACYP3A4ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342963-A | Optically active pyrrolidine derivative | AJINOMOTO CO., INC. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0513398-A1 | INTERMEDIATE FOR SYNTHESIS OF CARBAPENEM AND PRODUCTION OF SAID INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 1992-11-19 | — | — | EP | disclosed |