Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2045230 | 0.88 | ALOX5 (0.50) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL11884832 | 0.86 | ALOX5 (0.48) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| Acetic Acid SCHEMBL10948107 | 0.78 | ALOX5 (0.46) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL7915883 | 0.78 | ALOX5 (0.46) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL5655247 | 0.78 | — | — | |
| SCHEMBL5272054 | 0.76 | ALOX5 (0.45) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL5273332 | 0.76 | ALOX5 (0.50) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL15151279 | 0.76 | ALOX5 (0.50) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL11401370 | 0.74 | ALOX5 (0.38) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL8903967 | 0.73 | ALOX5 (0.50) | ALOX5SIGMAR1HTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356880-A | Glycyrrhetinic acid derivatives | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0548798-A1 | Antiviral agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| EP-0539180-A1 | Antiviral agents | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| EP-0518533-A1 | Glycyrrhetinic acid derivatives and antiviral compositions thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |