Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | G6PD | P11413 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884832 | 0.93 | ALOX5 (0.48) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| Acetic Acid SCHEMBL10948107 | 0.89 | ALOX5 (0.46) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL11401370 | 0.88 | ALOX5 (0.38) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL9347292 | 0.88 | ALOX5 (0.50) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL24527382 | 0.78 | KDM4E (0.40) | HTR3AALDH1A1TSHRHTR1AHTR7 | |
| SCHEMBL28290847 | 0.78 | ADRB2 (0.53) | CYP2D6ALDH1A1CYP3A4CYP1A2TSHR | |
| SCHEMBL28030097 | 0.78 | ADRB1 (0.53) | ALOX5ADRB1HTR3AALDH1A1HTR1A | |
| SCHEMBL28030091 | 0.78 | HTR3A (0.53) | ALOX5SIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL28236696 | 0.78 | CHRNB2 (0.38) | ALOX5ADRB1USP2L3MBTL1CHRNB2 | |
| SCHEMBL4722355 | 0.78 | ALOX5 (0.32) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021111448-A1 | COMPOSITIONS FOR PATTERNING A METAL ON A SUBSTRATE AND METHODS OF USING SAME | SCODIX LTD. (IL) | 2021-06-10 | — | — | WO | claimed |
| US-4662905-A | REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE | Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) | 1987-05-05 | — | — | US | claimed |
| US-4440696-A | FROM A PHENOL AND PHOSPHORUS TRIHALIDE, AMINE OR AMIDE CATALYST | CIBA-GEIGY CORPORATION (US) | 1984-04-03 | — | — | US | claimed |
| US-4390606-A | Color-forming para-sulfonamidodiphenylamine dye precursor and sulfonimide dye in photographic material and process | EASTMAN KODAK COMPANY (US) | 1983-06-28 | — | — | US | claimed |
| JP-6332100-A | — | — | None | — | — | JP | disclosed |
| JP-62212651-A | — | — | None | — | — | JP | disclosed |
| JP-5117239-A | — | — | None | — | — | JP | disclosed |
| US-11807646-B2 | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (USP19) | ALMAC DISCOVERY LIMITED (GB) | 2023-11-07 | — | — | US | disclosed |
| EP-3746432-B1 | 4-HYDROXYPIPERIDINE DERIVATIVES AND THEIR USE AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LTD (GB) | 2022-12-14 | — | — | EP | disclosed |
| US-20220033397-A1 | PHARMACEUTICAL COMPOUNDS AND THEIR USE AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | ALMAC DISCOVERY LTD (GB) | 2022-02-03 | — | — | US | disclosed |
| EP-3890829-A1 | PHARMACEUTICAL COMPOUNDS AND THEIR USE AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | Almac Discovery Limited (GB) | 2021-10-13 | — | — | EP | disclosed |
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | disclosed |
| US-RE30199-E | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |
| US-4168168-A | SILVER HALIDE EMULSIONS, SILVER IMAGE DIFFUSION OF SILVER OR COPPER IONS INTO GLASS SUPPORT | FUJI PHOTO FILM CO., LTD. (JP) | 1979-09-18 | — | — | US | disclosed |
| EP-0000757-A1 | Process for the preparation of triarylphosphites | CIBA-GEIGY AG (CH) | 1979-02-21 | — | — | EP | disclosed |
| US-RE29498-E | PEROXIDASE ENZYME SYSTEM | Istituto Sieroterapico e Vaccinogeno Toscano "SCLAVO", S.p.A. (IT) | 1977-12-20 | — | — | US | disclosed |
| US-4045458-A | FRIEDEL-CRAFTS CATALYSTS | KANZAKI PAPER MANUFACTURING CO., LTD. (JA) | 1977-08-30 | — | — | US | disclosed |
| US-4003699-A | Oxidation hair dyes based upon tetraaminopyrimidine developers | HENKEL & CIE G.M.B.H. (DT) | 1977-01-18 | — | — | US | disclosed |
| US-3966801-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1976-06-29 | — | — | US | disclosed |
| US-3930671-A | Color former and pressure-sensitive copying paper | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220033397-A1 | PHARMACEUTICAL COMPOUNDS AND THEIR USE AS INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 19 (USP19) | USP19, USP16, USP18 | ALOX5 3521/4885SIGMAR1 4703/4885HTR3E 3932/4885 |
| US-11807646-B2 | 4-hydroxypiperidine derivatives and their use as inhibitors of ubiquitin specific protease 19 (USP19) | USP19, USP16, USP18 | ALOX5 3847/4885SIGMAR1 4079/4885HTR3E 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.