Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9414627 | 0.76 | GABRA5 (0.32) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL9330104 | 0.75 | HSD17B10 (0.38) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL7196645 | 0.73 | SMN1; SMN2 (0.39) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL10778135 | 0.71 | GABRA5 (0.42) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL9332057 | 0.69 | SMN1; SMN2 (0.35) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL10405213 | 0.68 | SMN1; SMN2 (0.38) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL9331540 | 0.68 | HSD17B10 (0.36) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL27383162 | 0.68 | — | — | |
| SCHEMBL10777517 | 0.67 | ALDH1A1 (0.37) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 | |
| SCHEMBL9331561 | 0.67 | PIK3CG (0.39) | GABRA5GABRB2HSD17B10NOS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |