SCHEMBL934786

SCHEMBL934786

O=C(O)CN1CCNCCNCCNCC1

nearest known ligand 0.95

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.50
CHRM3 P20309 2/20 0.50
HSD17B10 Q99714 1/20 0.50
SIGMAR1 Q99720 6/20 0.46
CXCR4 P61073 2/20 0.39
CA2 P00918 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
CHKA P35790 1/20 0.37
KDM5C P41229 1/20 0.37
KDM4C Q9H3R0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472190 1.00 CHRM5 (0.50) CHRM5CHRM3HSD17B10SIGMAR1CXCR4
Piperazine SCHEMBL28199664 1.00 CHRM5 (0.50) CHRM5CHRM3HSD17B10SIGMAR1CXCR4
SCHEMBL29832951 0.98 CHRM5 (0.48) CHRM5CHRM3HSD17B10SIGMAR1CXCR4
SCHEMBL5550813 0.98 CHRM5 (0.48) CHRM5CHRM3HSD17B10SIGMAR1CXCR4
SCHEMBL29604422 0.98 CHRM5 (0.48) CHRM5CHRM3HSD17B10SIGMAR1CXCR4
SCHEMBL337070 0.98 HSD17B10 (0.52) CHRM5CHRM3HSD17B10SIGMAR1CA2
SCHEMBL62990 0.98 HSD17B10 (0.52) CHRM5CHRM3HSD17B10SIGMAR1CA2
SCHEMBL5556374 0.96 CHRM5 (0.47) CHRM5CHRM3HSD17B10SIGMAR1CXCR4
Hydrochloric Acid SCHEMBL1373260 0.95 CHRM5 (0.50) CHRM5CHRM3HSD17B10SIGMAR1CA2
SCHEMBL472213 0.95 CHRM5 (0.50) CHRM5CHRM3HSD17B10SIGMAR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025199636-A1 TARGETED RADIOLIGAND COMPOUNDS AND USES THEREOF MCMASTER UNIVERSITY (CA) 2025-10-02 WO claimed
EP-4556029-A2 RADIOPHARMACEUTICAL CONJUGATE The South African Nuclear Energy Corporation Limited (ZA) 2025-05-21 EP claimed
CN-119855612-A Radionuclide coupling medicine, pharmaceutical composition and application thereof 同宜医药(苏州)有限公司 2025-04-18 CN claimed
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2025-03-27 US claimed
US-20250026739-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2025-01-23 US claimed
EP-4479040-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF Full-Life Technologies HK Limited (HK) 2024-12-25 EP claimed
US-20240382630-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF FULL-LIFE TECHNOLOGIES UK LIMITED (GB) 2024-11-21 US claimed
US-12145926-B2 Compounds and radioligands for targeting neurotensin receptor and uses thereof FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-11-19 US claimed
EP-4436979-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies HK Limited (HK) 2024-10-02 EP claimed
US-20240287046-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF FULL-LIFE TECHNOLOGIES HK LIMITED (CN) 2024-08-29 US claimed
US-7226578-B2 Metal complexes that contain perfluoroalkyl, process for their production and their use in NMR diagnosis SHERING AG (DE) 2007-06-05 US claimed
EP-1602649-A2 1,4,7,10-TETRAAZACYCLODODECANE-1,4-DIACETIC ACID DERIVATIVES AS CHELATING AGENTS BRACCO S.p.A. (IT) 2005-12-07 EP claimed
EP-0998476-B1 1,4,7,10-TETRAAZABICYCLO 8.2.2]TETRADECAN-2-ONE, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR THE PREPARATION OF TETRAAZAMACROCYCLES BRACCO SPA (IT) 2004-05-06 EP claimed
US-6342597-B1 CONDENSATION REACTION TRIETHYLENETETRAMINE WITH GLYOXAL TO CYCLIZE; OXIDATION, ALKYLATION, HYDROLYSIS, QUATERNIZATION; NUCLEAR MAGNETIC RESONANCE IMAGING DIBRA S.P.A. (IT) 2002-01-29 US claimed
EP-0882010-B1 PHARMACEUTICAL AGENTS CONTAINING PERFLUOROALKYL-CONTAINING METAL COMPLEXES AND THE USE THEREOF IN TUMOUR THERAPY AND INTERVENTIONAL RADIOLOGY SCHERING AG (DE) 2001-05-02 EP claimed
EP-1047677-A2 Process for the preparation of derivatives of 1,4,7,10-tetraazacyclododecane-1,4-diacetic acid BRACCO S.p.A. (IT) 2000-11-02 EP claimed
EP-0998476-A1 1,4,7,10-TETRAAZABICYCLO 8.2.2]TETRADECAN-2-ONE, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR THE PREPARATION OF TETRAAZAMACROCYCLES BRACCO S.p.A. (IT) 2000-05-10 EP claimed
US-6020485-A Process for producing tetraazabicyclo monoacetic acid DIBRA S.P.A. (IT) 2000-02-01 US claimed
WO-1999035133-A2 1,4,7,10-TETRAAZACYCLODODECANE-1,4-DIACETIC ACID DERIVATIVES AS CHELATING AGENTS BRACCO S.P.A. (IT) 1999-07-15 WO claimed
WO-1999005145-A1 1,4,7,10-TETRAAZABICYCLO[8.2.2]TETRADECAN-2-ONE, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR THE PREPARATION OF TETRAAZAMACROCYCLES BRACCO S.P.A. (IT) 1999-02-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250026739-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF NTSR1, NTSR2, NPSR1 CHRM5 683/4885CHRM3 346/4885HSD17B10 2840/4885
US-20240382630-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR CHRM5 1306/4885CHRM3 642/4885HSD17B10 2591/4885
US-20240287046-A1 COMPOUNDS AND RADIOLIGANDS FOR TARGETING NEUROTENSIN RECEPTOR AND USES THEREOF NTSR1, NTSR2, NPSR1 CHRM5 717/4885CHRM3 368/4885HSD17B10 2630/4885
US-20250099632-A1 CLEAVABLE RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF ASGR1, GNRHR, SCTR CHRM5 1306/4885CHRM3 642/4885HSD17B10 2591/4885
US-12145926-B2 Compounds and radioligands for targeting neurotensin receptor and uses thereof NTSR1, NTSR2, NPSR1 CHRM5 717/4885CHRM3 368/4885HSD17B10 2630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.