SCHEMBL337070

SCHEMBL337070

O=C(O)CN1CCNCCN(CC(=O)O)CCNCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.52
CHRM5 P08912 2/20 0.52
CHRM3 P20309 2/20 0.52
SIGMAR1 Q99720 6/20 0.47
CA2 P00918 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA9 Q16790 1/20 0.39
CHKA P35790 1/20 0.38
KDM5C P41229 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
SLC6A9 P48067 1/20 0.37
POLB P06746 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL62990 1.00 HSD17B10 (0.52) HSD17B10CHRM5CHRM3SIGMAR1CA2
Hydrochloric Acid SCHEMBL31505485 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
Water SCHEMBL4953290 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
SCHEMBL29299554 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
SCHEMBL472190 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
SCHEMBL472213 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
Hydrochloric Acid SCHEMBL4441607 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
SCHEMBL306395 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
Hydrochloric Acid SCHEMBL1373260 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2
SCHEMBL934786 0.98 CHRM5 (0.50) HSD17B10CHRM5CHRM3SIGMAR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 314 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US claimed
US-20260097139-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GnRHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-04-09 US claimed
EP-4721765-A1 BI-FUNCTIONALIZED ANTIBODY CONJUGATES AGAINST THE ENDOTHELIN RECEPTOR B Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) 2026-04-08 EP claimed
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 US claimed
EP-4634174-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GNRHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-10-22 EP claimed
WO-2025217074-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2025-10-16 WO claimed
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-10-09 US claimed
EP-4622966-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-10-01 EP claimed
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 EP claimed
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-07-03 US claimed
WO-2012079582-A1 ENTRAPMENT OF RADIONUCLIDES IN NANOPARTICLE COMPOSITIONS TECHNICAL UNIVERSITY OF DENMARK (DK) 2012-06-21 WO claimed
EP-2453927-A1 LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES Technical University of Denmark (DK) 2012-05-23 EP claimed
EP-0998476-B1 1,4,7,10-TETRAAZABICYCLO 8.2.2]TETRADECAN-2-ONE, A PROCESS FOR THE PREPARATION THEREOF AND THE USE THEREOF FOR THE PREPARATION OF TETRAAZAMACROCYCLES BRACCO SPA (IT) 2004-05-06 EP claimed
EP-0998466-B1 A PROCESS FOR THE PREPARATION OF TETRAAZAMACROCYCLES BRACCO IMAGING SPA (IT) 2002-10-16 EP claimed
US-6162912-A Process of preparing tetraacetic acid derivatives DIBRA S.P.A. (IT) 2000-12-19 US claimed
US-5922862-A Process for the preparation of tetraazamacrocycles DIBRA S.P.A. (IT) 1999-07-13 US claimed
US-5428155-A PH controlled sulfomethylation of 1,4,7,10-tetraazacyclododecane; displacement with sodium cyanide; hydrolysis to symmetrical acetic acid side groups BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-06-27 US claimed
EP-0618910-A1 SYNTHESIS OF POLYAZAMACROCYCLES WITH MORE THAN ONE TYPE OF SIDE-CHAIN CHELATING GROUPS THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-10-12 EP claimed
US-5316757-A MRI contrast agent BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1994-05-31 US claimed
WO-1993012097-A1 SYNTHESIS OF POLYAZAMACROCYCLES WITH MORE THAN ONE TYPE OF SIDE-CHAIN CHELATING GROUPS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1993-06-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097139-A1 GONADOTROPIN-RELEASING HORMONE RECEPTOR (GnRHR) TARGETED THERAPEUTICS AND USES THEREOF GNRHR, GHRHR, FSHR HSD17B10 1239/4885CHRM5 3447/4885CHRM3 3470/4885
US-20250213735-A1 NEUROPEPTIDE Y1 RECEPTOR (NPY1R) TARGETED THERAPEUTICS AND USES THEREOF NPY1R, NPY2R, NPY4R HSD17B10 3848/4885CHRM5 2123/4885CHRM3 1728/4885
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF KISS1R, GNRHR, PROKR1 HSD17B10 3643/4885CHRM5 4097/4885CHRM3 3211/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR HSD17B10 568/4885CHRM5 2940/4885CHRM3 2831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.