Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.81 |
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | ACACA | Q13085 | 3/20 | 0.47 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13140097 | 0.90 | ALOX5 (0.83) | ALOX5ACACBACACAHAO1EPHX2 | |
| SCHEMBL9046388 | 0.90 | ALOX5 (1.00) | ALOX5ACACBACACAEPHX2 | |
| SCHEMBL9175836 | 0.89 | ALOX5 (0.69) | ALOX5ACACBACACAHAO1EPHX2 | |
| SCHEMBL9351538 | 0.85 | ALOX5 (0.64) | ALOX5ACACBACACAHAO1PTGS1 | |
| SCHEMBL9047251 | 0.82 | ALOX5 (0.84) | ALOX5ACACBACACAEPHX2MEN1 | |
| SCHEMBL9048463 | 0.82 | ALOX5 (0.84) | ALOX5ACACBACACAEPHX2MEN1 | |
| SCHEMBL9047950 | 0.81 | ALOX5 (0.83) | ALOX5ACACBACACAEPHX2MEN1 | |
| Fenleuton SCHEMBL31539081 | 0.81 | ALOX5 (1.00) | ALOX5ACACBACACAEPHX2MEN1 | |
| Fenleuton SCHEMBL74861 | 0.81 | ALOX5 (1.00) | ALOX5ACACBACACAEPHX2MEN1 | |
| SCHEMBL9046519 | 0.81 | ALOX5 (0.83) | ALOX5ACACBACACAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6256285-A | — | — | None | — | — | JP | disclosed |
| JP-H06256285-A | HYDROXAMIC ACID DERIVATIVE AND ITS USE | PFIZER PHARMACEUT CO LTD | 1994-09-13 | — | — | JP | disclosed |
| EP-0561882-B1 | HYDROXAMIC ACID DERIVATIVES WHICH INHIBIT LIPOXYGENASE | PFIZER (US) | 1994-08-31 | — | — | EP | disclosed |