Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.39 |
| ▸ | ACACA | Q13085 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348010 | 0.81 | ACACB (0.42) | ACACBACACAALOX5MTNR1APTGS1 | |
| SCHEMBL9348080 | 0.78 | ALOX5 (0.53) | ACACBACACAALOX5MTNR1APTGS1 | |
| SCHEMBL9347565 | 0.76 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL9351423 | 0.75 | ALOX5 (0.44) | ACACBACACAALOX5 | |
| SCHEMBL9450774 | 0.73 | ALOX5 (0.45) | ACACBACACAALOX5MTNR1APTGS1 | |
| SCHEMBL9351417 | 0.69 | ALOX5 (0.36) | ACACBACACAALOX5 | |
| SCHEMBL8707586 | 0.69 | ACACB (0.33) | ACACB | |
| SCHEMBL8707088 | 0.69 | BCL2A1 (0.34) | ACACB | |
| SCHEMBL8707083 | 0.69 | BCL2A1 (0.34) | ACACB | |
| SCHEMBL8707360 | 0.69 | EPHX2 (0.34) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561882-B1 | HYDROXAMIC ACID DERIVATIVES WHICH INHIBIT LIPOXYGENASE | PFIZER (US) | 1994-08-31 | — | — | EP | disclosed |