Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348080 | 0.87 | ALOX5 (0.53) | ACACBACACAALOX5PTGS1PTGS2 | |
| SCHEMBL9347565 | 0.81 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL9348140 | 0.81 | ACACB (0.39) | ACACBACACAALOX5PTGS1PTGS2 | |
| SCHEMBL9351538 | 0.80 | ALOX5 (0.64) | ACACBACACAALOX5PTGS1PTGS2 | |
| SCHEMBL9450774 | 0.75 | ALOX5 (0.45) | ACACBACACAALOX5PTGS1PTGS2 | |
| SCHEMBL9348018 | 0.66 | ALOX5 (0.81) | ACACBACACAALOX5PTGS1PTGS2 | |
| SCHEMBL6063354 | 0.65 | CYP3A4 (0.53) | ACACBPTGS1PTGS2MTNR1AKAT6A | |
| SCHEMBL5799392 | 0.65 | KAT6A (0.54) | KAT6AOPRM1OPRK1KCNH2 | |
| SCHEMBL11663045 | 0.65 | SLC6A4 (0.47) | MTNR1AKAT6AOPRM1OPRK1KCNH2 | |
| SCHEMBL6496199 | 0.64 | SLC6A2 (0.66) | KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561882-B1 | HYDROXAMIC ACID DERIVATIVES WHICH INHIBIT LIPOXYGENASE | PFIZER (US) | 1994-08-31 | — | — | EP | disclosed |