Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352368 | 0.85 | PGR (0.42) | MGLLMAPTALDH1A1CYP1A2KMT2A | |
| SCHEMBL9348203 | 0.84 | NPC1 (0.40) | MAPTNPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9628950 | 0.83 | MAPT (0.38) | MGLLMAPTNPC1KAT2BBCHE | |
| SCHEMBL9348254 | 0.83 | PGR (0.43) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL9348253 | 0.80 | POLB (0.44) | NPC1ALDH1A1CYP1A2KMT2AMEN1 | |
| SCHEMBL10377268 | 0.80 | CACNA2D1 (0.41) | MAPTNPC1KAT2BBCHECYP1A2 | |
| SCHEMBL9348086 | 0.80 | PGR (0.44) | MAPTNPC1KAT2BALDH1A1CYP1A2 | |
| SCHEMBL9348228 | 0.78 | PGR (0.55) | MAPTKAT2BKMT2AMEN1HPGD | |
| SCHEMBL10686019 | 0.73 | CACNA2D1 (0.41) | MGLLMAPTNPC1KAT2BALDH1A1 | |
| SCHEMBL10688176 | 0.72 | CACNA2D1 (0.43) | MGLLMAPTNPC1KAT2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338010-B1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HYPERPROLIFERATE SKIN DISEASE | SCHERING CORPORATION (US) | 1992-02-05 | — | — | EP | claimed |
| EP-0228416-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AZANAPHTHALENES | SCHERING CORPORATION (US) | 1990-03-21 | — | — | EP | claimed |
| EP-0144996-B1 | SUBSTITUTED SPIRO PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1990-02-28 | — | — | EP | claimed |
| EP-0338010-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HYPERPROLIFERATE SKIN DISEASE. | SCHERING CORP (US) | 1989-10-25 | — | — | EP | claimed |
| WO-1988004172-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HYPERPROLIFERATE SKIN DISEASE | SCHERING CORPORATION (US) | 1988-06-16 | — | — | WO | claimed |
| EP-0228416-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AZANAPHTHALENES. | SCHERING CORP (US) | 1987-07-15 | — | — | EP | claimed |
| WO-1986007537-A2 | PHARMACEUTICAL COMPOSITIONS CONTAINING AZANAPHTHALENES | SCHERING CORPORATION (US) | 1986-12-31 | — | — | WO | claimed |
| EP-0144996-A2 | Substituted spiro pyridine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions | SCHERING CORPORATION (US) | 1985-06-19 | — | — | EP | claimed |
| US-5350755-A | Treatment of psoriasis or eczema with naphthyridine derivative | SCHERING CORPORATION (US) | 1994-09-27 | — | — | US | disclosed |
| EP-0144996-B1 | SUBSTITUTED SPIRO PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THE PREPARATION OF SUCH COMPOUNDS AND COMPOSITIONS | SCHERING CORPORATION (US) | 1990-02-28 | — | — | EP | disclosed |
| US-4652564-A | Substituted spiro pyridine derivatives as anti-allergy and antiinflammatory agents | SCHERING CORPORATION (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0144996-A2 | Substituted spiro pyridine derivatives, pharmaceutical compositions containing them and processes for the preparation of such compounds and compositions | SCHERING CORPORATION (US) | 1985-06-19 | — | — | EP | disclosed |