Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.36 |
| ▸ | IAPP | P10997 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348257 | 0.87 | CA2 (0.47) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL6559322 | 0.83 | GABRA1 (0.61) | CA2GABRA1GABRB2TSHRCYP1A2 | |
| SCHEMBL8324365 | 0.82 | GABRA1 (0.68) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL9348414 | 0.80 | GABRA1 (0.65) | GABRA1GABRB2IAPPDHODH | |
| SCHEMBL7065972 | 0.80 | CA2 (0.59) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL3809080 | 0.80 | CA2 (0.59) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL430927 | 0.79 | CA2 (0.57) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL6345729 | 0.78 | IAPP (0.55) | CA2GABRA1GABRB2ALDH1A1TDP1 | |
| SCHEMBL9994746 | 0.78 | CA2 (0.61) | CA2GABRA1GABRB2ATMALOX12 | |
| SCHEMBL57139 | 0.77 | GABRA1 (0.67) | CA2GABRA1GABRB2ATMALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100516031-C | Organic multiple isocyanate composition | MITSUI TAKEDA CHEMICAL CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-1626509-A | Organic multiple isocyanate compsn. | MITSUI TAKEDA CHEMICAL CO LTD (JP) | 2005-06-15 | — | — | CN | disclosed |
| EP-0258598-B1 | N-(substituted-1-piperazinealkyl)-alpha-(3,5-di-alkyl-4-hydroxyphenyl)-alpha,alpha-dialkyl acetamides | GOODRICH CO B F (US) | 1994-09-07 | — | — | EP | disclosed |
| CN-1022915-C | Process for preparing N, alpha-substituted acetamide | GOODRICH CO B F (US) | 1993-12-01 | — | — | CN | disclosed |
| EP-0253010-B1 | N-(SUBSTITUTED CYCLIC ALKYLENEIMINE)-ALPHA-(3,5-DI-ALKYL-4-HYDROXY-PHENYL)-ALPHA, ALPHA-DIALKYL ACETAMIDES | The B.F. GOODRICH Company (US) | 1992-12-02 | — | — | EP | disclosed |
| US-5096949-A | Heat and oxidation resistance, photostability; polyolefins; uv rad | THE B. F. GOODRICH COMPANY (US) | 1992-03-17 | — | — | US | disclosed |
| US-4920228-A | N,N-disubstituted, α-(3,5-dialkyl-4-hydroxyphenyl)-α,α-disubstituted acetamides and composition stabilized therewith | THE B. F. GOODRICH COMPANY (US) | 1990-04-24 | — | — | US | disclosed |
| US-4780495-A | HEAT, OXIDATION, AND LIGHT STABILIZERS | THE B. F. GOODRICH COMPANY (US) | 1988-10-25 | — | — | US | disclosed |
| EP-0284800-A1 | N-(substituted piperidinyl)-alpha-(3,5-dialkyl-4-hydroxyphenyl)-alpha', alpha''-dialkyl acetamides | THE B.F. GOODRICH COMPANY (US) | 1988-10-05 | — | — | EP | disclosed |
| EP-0141419-B1 | 3,5-DIALKYL-4-HYDROXYPHENYL-SUBSTITUTED DERIVATIVES | The B.F. GOODRICH Company (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0258598-A2 | N-(substituted-1-piperazinealkyl)-alpha-(3,5-di-alkyl-4-hydroxyphenyl)-alpha,alpha-dialkyl acetamides | THE B.F. GOODRICH COMPANY (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0253010-A1 | N-(substituted cyclic alkyleneimine)-alpha-(3,5-di-alkyl-4-hydroxy-phenyl)-alpha, alpha-dialkyl acetamides | The B.F. GOODRICH Company (US) | 1988-01-20 | — | — | EP | disclosed |
| US-4523032-A | 3,5-Dialkyl-4-hydroxyphenyl-substituted acetic acids | THE B. F. GOODRICH COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0141419-A1 | 3,5-Dialkyl-4-hydroxyphenyl-substituted derivatives | The B.F. GOODRICH Company (US) | 1985-05-15 | — | — | EP | disclosed |